Location, Location, Location: Is Membrane Partitioning Everything When It Comes to Innate Immune Activation?

Location, Location, Location: Is Membrane Partitioning Everything When It Comes to Innate Immune Activation?

In the last twenty years, the general view of the plasma membrane has changed from a homogeneous arrangement of lipids to a mosaic of microdomains. It is currently thought that islands of highly ordered saturated lipids and cholesterol, which are laterally mobile, exist in the plane of the plasma membrane. Lipid rafts are thought to provide a means to explain the spatial segregation of certain ...

When It Comes to Frizzled-Mediated Developmental Pathways, Location Matters

When It Comes to Electric Vehicle Emissions, Location Matters

FDA Delays Enforcement of New Sunscreen Labels When the U.S. FDA announced new rules for sunscreen labeling in June 2011, manufacturers were given a year to comply. In May 2012 the agency announced a six-month delay in enforcement to give manufacturers extra time to retool labels and complete broad-spectrum testing for their products. Under the new regulations, sunscreen products including cosm...

Location is everything

Location, Location, Location . . . It Is Important in Pancreatitis, Too

he phrase “location, location, location” has been Tused in the real estate business for more than 90 years to convey the overriding importance of location in determining value, function, and opportunity. It now may be important in how we approach pancreatitis. Pancreatitis is a painful and often debilitating disease for which there are no specific or effective treatments. Although patient morta...